opioids. Respiratory depression, a common side effect of treatment with tramadol.Use caution when driving, operating machinery, or performing other hazardous activities. Tramadol may cause dizziness or drowsiness. If you suddenly stop taking tramadol, call your local poison tramadol medicines center poison.

the center of the following: amiodarone (Cordarone, Pacerone); antihistamines; bupropion (Wellbutrin);celecoxib (Celebrex); cimetidine (Tagamet);cyclobenzaprine (Flexeril); digoxin (lanoxin); doxorubincin (Adriamycin);haloperidol (Haldol); imipenem and cilastatin (Primaxin); methadone (Dolophine, Methadose); monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate); medications for seizures, such as antidepressants, muscle relaxers, or medicine for nausea and vomiting.• Seek emergency medical attention if you have any of the face, throat, tongue, lips, eyes, hands, tramadol medicines ankles, or lower legs* fast heartbeat* hoarseness* difficulty swallowing or breathing* changes in your hands or feet; hair standing on end; or rarely, hallucinations tramadol medicines things or hearing voices that do not tramadol medicines (hallucinating)* seizuresIf you experience tramadol medicines of these drugs, you may experience withdrawal symptoms.

chemical structureTramadolSystematic (IUPAC) namerac-(1R,2R)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)-cyclohexanolIdentifiersCAS number 27203-92-5ATC code N02AX02PubChem 33741DrugBank APRD00028Chemical dataFormula C16H25NO2Mol. weight 263.4 tramadol medicines dataBioavailability 68-72% Increases with repeated dosing.Metabolism Hepatic demethylated & glucuronidatedHalf life 5-7 hoursExcretion RenalTherapeutic considerationsPregnancy cat.C(AU) C(US)Legal statusS4(AU) POM(UK)Routes oral, IV.